Pituitary Hormone Replacement Therapy

Today, I read Medicine journal as follows.

Source: Claire Higham, Stephen Shalet, Peter J Trainer, Medicine Vol 37;8, August 2009, Page 399 (www.medicinejournal.co.uk )

Growth Hormone deficiency

Growth hormone

  • 0.3-1 mg s.c in the eveining

Gonadotropins deficiency

For wome:

  • (Oestradial valeate  1-2 mg daily PO or Conjugated equine oestrogens 0.625-a.25 mcg daily PO)  plus Progesterone (Dose depends on preparation used)

For men:

IM

  • Testosterone ester (Sustanon) 250 mg IM every 2-3 weeks
  • Testtosterone undcanoate 1000mg/12 weeks

Transdermal

  • Patch 5-7.5 mg /24 hrs
  • Gel sachet 50 mg/5g sachet/24 hours
  • Gel dispenser 30 mg/12 hrs

Buccal

  • 30 mg/12 hrs

TSH deficiency

Thyroxine

  • 75-150 mcg daily

ACTH deficiency

Hydrocortisone

  • 10 mg morning, 5 mg noon, 5 mg evening

Prolactin

  • Nil

ADH deficiency

Desmopressin

  • 10-40 mcg intranasally in 2-3 divided doses
  • 300-600 mcg daily PO in 2-3 divided doses

Thanks